AWS HealthOmics variant stores and annotation stores will no longer be open to new customers starting November 7th, 2025. If you would like to use variant stores or annotation stores, sign up prior to that date. Existing customers can continue to use the service as normal. For more information, see AWS HealthOmics variant store and annotation store availability change.

HealthOmics Resource permissions

AWS HealthOmics creates and accesses resources in other services on your behalf when you run a job or create a store. In some cases, you need to configure permissions in other services to access resources or to allow HealthOmics to access them.

For resource permissions related to Amazon ECR, see Amazon ECR permissions.

Lake Formation permissions

Before you use analytics features in HealthOmics, configure default database settings in Lake Formation.

HealthOmics Analytics auto accepts data if your service policy has the correct RAM permissions, such as the following example.

JSON

{
  "Version":"2012-10-17",		 	 	 
  "Statement": [
    {
      "Effect": "Allow",
      "Action": [
        "omics:*"
      ],
      "Resource": "*"
    },
    {
      "Effect": "Allow",
      "Action": [
        "ram:AcceptResourceShareInvitation",
        "ram:GetResourceShareInvitations"
      ],
      "Resource": "*"
    }
  ]
}