# Compute and hardware
<a name="compute-and-hardware"></a>


|  LSPERF05: How do you choose compute for life science workloads like molecular modeling, genomics, bioinformatics, and AI drug discovery?  | 
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 Explore strategies for matching specialized life sciences workloads with optimal computational resources to enhance performance and efficiency across molecular modeling, genomics, and AI-driven research applications. 


|  LSPERF06: What process do you follow to evaluate specialized hardware accelerators for molecular dynamics simulations or genomic analysis?  | 
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 Implement a systematic approach to evaluating specialized hardware accelerators for optimal performance in molecular dynamics simulations and genomic analysis. 


|  LSPERF07: How do you balance high-performance computing needs with GxP requirements?  | 
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 Life sciences organizations face the challenge of balancing computational power with GxP adherence. Explore strategies for creating validated computing environments that meet both scientific needs and regulatory requirements. Topics include infrastructure design, validation approaches, data integrity, and change management that enables innovation within frameworks. Learn practical methods for optimizing performance while successfully navigating GxP regulations in life sciences applications. 


|  LSPERF08: What metrics do you monitor to verify if compute resources meet the performance demands of time-sensitive clinical applications?  | 
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 Key performance metrics and monitoring protocols for verifying that compute resources consistently meet the demands of time-critical clinical applications. This discussion covers essential technical indicators, threshold management, and proactive monitoring strategies specifically tailored for clinical environments where application performance directly impacts patient care, diagnostic accuracy, and treatment delivery. 

**Topics**
+ [LSPERF05-BP01 Specialized hardware matching](lsperf05-bp01.md)
+ [LSPERF05-BP02 Establish a tiered infrastructure strategy](lsperf05-bp02.md)
+ [LSPERF05-BP03 Implement a comprehensive system optimization strategy](lsperf05-bp03.md)
+ [LSPERF06-BP01 Run comprehensive, benchmark-driven assessments](lsperf06-bp01.md)
+ [LSPERF06-BP02 Perform a total cost of ownership analysis](lsperf06-bp02.md)
+ [LSPERF06-BP03 Perform an environment compatibility validation](lsperf06-bp03.md)
+ [LSPERF07-BP01 Use a risk-based validation framework](lsperf07-bp01.md)
+ [LSPERF07-BP02 Design a compliant-by-design infrastructure](lsperf07-bp02.md)
+ [LSPERF07-BP03 Develop an agile change management process](lsperf07-bp03.md)
+ [LSPERF08-BP01 Implement holistic system performance monitoring beyond traditional latency metrics](lsperf08-bp01.md)
+ [LSPERF08-BP02 Track resource utilization with clinical context](lsperf08-bp02.md)
+ [LSPERF08-BP03 Implement clinical system monitoring with workflow validation and impact analysis](lsperf08-bp03.md)